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Article

Beta-catenin-mediated cell-adhesion is vital for embryonic forebrain development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2005

Junghans Dirk, Hack Iris, Frotscher Michael, Taylor Verdon, Kemler Rolf

Abstract excerpt

Forming a complex structure such as the mammalian brain requires a complex interplay between cells and different signalling cascades during embryonic development. beta-catenin plays pivotal roles in these processes by mediating cadherin-based cell adhesion and Wnt signalling. We show for the first time that beta-catenin functions predominantly as a mediator of cell adhesion during early development of the...

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PMID: 15844200
DOI: 10.1002/dvdy.20365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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