Article
E-cadherin is required for cranial neural crest migration in Xenopus laevis.
Developmental biology - 15 Mar 2016
Huang Chaolie, Kratzer Marie-Claire, Wedlich Doris, Kashef Jubin
Abstract excerpt
The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on defined routes throughout the embryo, contributing to facial structures including cartilage, bone and ganglia. Cadherin-mediated cell-cell adhesion is known to play a crucial role in the directional migration of CNC cells. However, migrating CNC co-express different cadherin subtypes, and...
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