Article
Molecular genetics of neuronal adhesion.
Current opinion in neurobiology - 1 Feb 1995
Müller U, Kypta R
Abstract excerpt
Cell-cell and cell-matrix interactions are believed to play crucial roles in neural development. Cell adhesion molecules of the immunoglobulin and cadherin families, as well as integrin heterodimers and extracellular matrix glycoproteins, are widely expressed in the nervous system. The advent of gene targeting technology has heralded a new era for study of their function. Initial observations in 'knockout' mice...
Topics
- Animals
- Cadherins
- Cell Adhesion Molecules
- Cell Adhesion Molecules, Neuronal
- Cell Communication
- Gene Targeting
- Integrins
- Mutation
- Myelin Proteins
- Nervous System Physiological Phenomena
- Neuroglia