Article
Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.
BMC biology - 11 Apr 2015
Gay Max Hans-Peter, Valenta Tomas, Herr Patrick, Paratore-Hari Lisette, Basler Konrad, Sommer Lukas
Abstract excerpt
BACKGROUND: β-catenin plays a central role in multiple developmental processes. However, it has been difficult to study its pleiotropic effects, because of the dual capacity of β-catenin to coordinate cadherin-dependent cell adhesion and to act as a component of Wnt signal transduction. To distinguish between the divergent functions of β-catenin during peripheral nervous system development, we made use of a...
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