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Article

Genetic variation at the IL10 gene locus is associated with severity of respiratory syncytial virus bronchiolitis.

The Journal of infectious diseases - 15 May 2005

Wilson Jonathan, Rowlands Kate, Rockett Kirk, Moore Catrin, Lockhart Elizabeth, Sharland Mike, Kwiatkowski Dominic, Hull Jeremy

Abstract excerpt

The intense airway inflammatory response associated with respiratory syncytial virus (RSV) infection may be an important determinant in the severity of the disease. Interleukin (IL)-10 is a key regulatory cytokine known to be secreted during this infection. We investigated the role that IL-10 plays in RSV disease by studying the effects that variation in the IL10 gene has on the outcome of the disease. Eight...

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Identifiers

PMID: 15838798
DOI: 10.1086/429636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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