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Article

IL-10 gene polymorphism at -1082 A/G is associated with severe rhinovirus bronchiolitis in infants.

Pediatric pulmonology - 1 Apr 2008

Helminen Merja, Nuolivirta Kirsi, Virta Miia, Halkosalo Anne, Korppi Matti, Vesikari Timo, Hurme Mikko

Abstract excerpt

We analyzed polymorphisms of IL-10 -1082 G/A, IL-18 -137 G/C, TLR4 +896 A/G, and IFNG +874 T/A in 139 infants under 6 months of age hospitalized with bronchiolitis and 400 unselected blood donors. Causative viruses were determined by PCR. Infants with bronchiolitis associated with a virus other than respiratory syncytial virus (N = 18), were more often IL-10 -1082 allele G non-carriers, that is, homozygous for...

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Identifiers

PMID: 18286551
DOI: 10.1002/ppul.20793

Genes

IFNG
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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