Article
Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families.
Thorax - 1 Dec 2000
Hull J, Thomson A, Kwiatkowski D
Abstract excerpt
BACKGROUND: Respiratory syncytial virus (RSV) infects nearly all children by the end of their second winter. Why some develop bronchiolitis is poorly understood; it is not known whether there is a genetic component. The pathological features include neutrophil infiltration and high levels of interleukin 8 (IL-8), a potent neutrophil chemoattractant. METHODS: Common genetic variants of the promoter region of the...
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