Article
Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.
American journal of medical genetics. Part A - 15 Jun 2004
Royer-Pokora Brigitte, Beier Manfred, Henzler Markus, Alam Rita, Schumacher Valérie, Weirich Angela, Huff Vicki
Abstract excerpt
We report here 24 new Wilms tumor (WT) patients with germline WT1 alterations and a synopsis of our own previously described and literature cases in whom age of tumor-onset, gender, and laterality were known. This combined database contains 282 patients, 117 patients with and 165 without WT1 germline alterations. Using this information we have determined the median age of tumor-onset for patients with (12.5...
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