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Article

Application of logistic regression to case-control association studies involving two causative loci.

Human heredity - 1 Jan 2005

North Bernard V, Curtis David, Sham Pak C

Abstract excerpt

Models in which two susceptibility loci jointly influence the risk of developing disease can be explored using logistic regression analysis. Comparison of likelihoods of models incorporating different sets of disease model parameters allows inferences to be drawn regarding the nature of the joint effect of the loci. We have simulated case-control samples generated assuming different two-locus models and then...

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PMID: 15838177
DOI: 10.1159/000085222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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