Modelling the effects of genetic and environmental factors on the risk of autoimmune disease.

Abstract excerpt

The presence or absence of autoimmune disease is a qualitative outcome resulting from the combined influences of genetic, environmental and stochastic factors that interact in complex ways. Because of the nature of these interactions, the effects of risk factors that contribute to the aetiology of disease cannot be adequately assessed individually. Here, I propose an approach to multiparameter modelling of...

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