Article
Confirmation of genetic linkage between atopic IgE responses and chromosome 11q13.
Journal of medical genetics - 1 Apr 1992
Young R P, Sharp P A, Lynch J R, Faux J A, Lathrop G M, Cookson W O, Hopkin J M
Abstract excerpt
Genetic linkage between atopic IgE responses and chromosome 11q13 (D11S97) has been previously reported in a limited number of extended families. Difficulties of phenotyping in the older family members, poor family structure in some families, and genetic heterogeneity were proposed as possible explanations for the variability in lod scores. To test this finding a second linkage study of 64 young nuclear families...
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