Article
Linkage analysis of markers on chromosome 11q13 with asthma and atopy in a United Kingdom population.
American journal of respiratory and critical care medicine - 1 Oct 2000
Simon Thomas N, Wilkinson J, Lonjou C, Morton N E, Holgate S T
Abstract excerpt
Previous studies have suggested that atopy is linked to the beta chain of the high affinity IgE receptor (Fcepsilon R1-beta) on chromosome 11q13. Fcepsilon R1-beta polymorphisms, I181L, V183L, and E237G, are reported to be associated with asthma and atopy. The aim of this study was to investigate linkage to Fcepsilon R1-beta in a UK population and to assess the frequency of the polymorphisms and their association...
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