Article
Genetic analysis of atopy in three large kindreds: no evidence of linkage to D11S97.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 1992
Rich S S, Roitman-Johnson B, Greenberg B, Roberts S, Blumenthal M N
Abstract excerpt
Both genetic and environmental influences have been implicated in the pathogenesis of atopic disease. A recent report suggested that a major gene providing susceptibility to atopy was transmitted in a pattern consistent with autosomal dominant inheritance and evidence was presented that places the disease locus near the D11S97 marker on human chromosome 11q. In this report, we present three large, highly...
Topics
- Genetic Linkage
- Genetic Markers
- Genetic Techniques
- HLA Antigens
- Humans
- Hypersensitivity
- Pedigree
- Phenotype