Article
No association between insulin gene variation and adult metabolic phenotypes in a large Finnish birth cohort.
Diabetologia - 1 May 2005
Bennett A, Sovio U, Ruokonen A, Martikainen H, Pouta A, Taponen S, Hartikainen A-L, Franks S, Peltonen L, Elliott P, Järvelin M-R, McCarthy M I
Abstract excerpt
AIMS/HYPOTHESIS: Although the variable number tandem repeat (VNTR) minisatellite 5' to the insulin gene is among the most studied polymorphisms in diabetes, the relationships between VNTR variation, diabetes-related traits and predisposition to type 2 diabetes remain unclear. Since inadequate sample size is likely to have been an obstacle to reliable inference, we examined the relationship between VNTR variation...
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