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Article

Systematic gain-of-function genetics in Drosophila.

Development (Cambridge, England) - 1 Mar 1998

Rørth P, Szabo K, Bailey A, Laverty T, Rehm J, Rubin G M, Weigmann K, Milán M, Benes V, Ansorge W, Cohen S M

Abstract excerpt

A modular misexpression system was used to carry out systematic gain-of-function genetic screens in Drosophila. The system is based on inducible expression of genes tagged by insertion of a P-element vector carrying a GAL4-regulated promoter oriented to transcribe flanking genomic sequences. To identify genes involved in eye and wing development, the 2300 independent lines were screened for dominant phenotypes....

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Identifiers

PMID: 9463351
DOI: 10.1242/dev.125.6.1049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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