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Article

A TGF-beta1 polymorphism association with dementia and neuropathologies: the HAAS.

Neurobiology of aging - 1 Sept 2007

Peila Rita, Yucesoy Berran, White Lon R, Johnson Victor, Kashon Michael L, Wu Kim, Petrovitch Helen, Luster Michael, Launer Lenore J

Abstract excerpt

The transforming growth factor-beta1 (TGF-beta1) is involved in post-ischemic neuronal rescue and in beta-amyloid turn-over. We hypothesized that the risk for dementia and related neuropathologies is modified by the TGF-beta1 functional genetic variants. The association of the TGF-beta1+29T-->C polymorphism with dementia was examined in a sample of 261 cases and 491 controls from the Honolulu-Asia Aging Study,...

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Identifiers

PMID: 16904244
DOI: 10.1016/j.neurobiolaging.2006.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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