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Article

The gene encoding transforming growth factor beta 1 confers risk of ischemic stroke and vascular dementia.

Stroke - 1 Nov 2006

Kim Younyoung, Lee Chaeyoung

Abstract excerpt

BACKGROUND AND PURPOSE: Transforming growth factor-beta1 (TGF-beta1) is an anti-inflammatory cytokine that plays an important role in cerebrovascular pathophysiology with protective activity against ischemia-induced neuronal death. We investigated the association of the polymorphism in TGFB1 with ischemic stroke and vascular dementia. METHODS: Three sequence variants in and around promoter and exons of TGFB1 gene...

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Source

Identifiers

PMID: 16990569
DOI: 10.1161/01.STR.0000244782.76917.87

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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