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Article

Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

The Journal of biological chemistry - 17 Jun 2005

Chavan Manasi, Yan Aixin, Lennarz William J

Abstract excerpt

Following initiation of translocation across the membrane of the endoplasmic reticulum via the translocon, polypeptide chains are N-glycosylated by the oligosaccharyl transferase (OT) enzyme complex. Translocation and N-glycosylation are concurrent events and would be expected to require juxtaposition of the translocon and the OT complex. To determine whether any of the subunits of the OT complex and translocon...

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Identifiers

PMID: 15831493
DOI: 10.1074/jbc.M502858200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Subunits of the translocon interact with components of the oligosaccharyl transferase complex.PMID 15831493Read ↗

Two oligosaccharyl transferase complexes exist in yeast and associate with two different translocons.Semantic proximity Read ↗

Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase.Semantic proximity Read ↗

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.Semantic proximity Read ↗

The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex.Semantic proximity Read ↗

A specific segment of the transmembrane domain of Wbp1p is essential for its incorporation into the oligosaccharyl transferase complex.Semantic proximity Read ↗

Molecular architecture of the ER translocase probed by chemical crosslinking of Sss1p to complementary fragments of Sec61p.Semantic proximity Read ↗

Studies on the N-glycosylation of the subunits of oligosaccharyl transferase in Saccharomyces cerevisiae.Semantic proximity Read ↗

The STT3 protein is a component of the yeast oligosaccharyltransferase complex.Semantic proximity Read ↗

Studies on the function of oligosaccharyl transferase subunits. Stt3p is directly involved in the glycosylation process.Semantic proximity Read ↗

Polypeptide binding specificities of Saccharomyces cerevisiae oligosaccharyltransferase accessory proteins Ost3p and Ost6p.Semantic proximity Read ↗

Structural studies and the assembly of the heptameric post-translational translocon complex.Semantic proximity Read ↗

The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1.Semantic proximity Read ↗

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