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Article

Changes in composition of caecal microbiota associated with increased colon inflammation in interleukin-10 gene-deficient mice inoculated with Enterococcus species.

Nutrients - 11 Mar 2015

Bassett Shalome A, Young Wayne, Barnett Matthew P G, Cookson Adrian L, McNabb Warren C, Roy Nicole C

Abstract excerpt

Human inflammatory bowel disease (IBD) is a chronic intestinal disease where the resident microbiota contributes to disease development, yet the specific mechanisms remain unclear. Interleukin-10 gene-deficient (Il10-/-) mice develop inflammation similar to IBD, due in part to an inappropriate response to commensal bacteria. We have previously reported changes in intestinal morphology and colonic gene expression...

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Identifiers

PMID: 25768951
DOI: 10.3390/nu7031798
PMCID: PMC4377882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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