Article
Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations.
AIDS (London, England) - 29 Apr 2005
Johnston Elizabeth, Dupnik Kathryn M, Gonzales Matthew J, Winters Mark A, Rhee Soo-Yon, Imamichi Tomozumi, Shafer Robert W
Abstract excerpt
We have created a panel of recombinant HIV-1 infectious clones containing common patterns of reverse transcriptase (RT) mutations responsible for resistance to each of the currently available nucleoside reverse transcriptase inhibitors (NRTI), and we have submitted the panel to the National Institutes of Health AIDS Research and Reference Reagent Programme. Testing the activity of new antiretroviral compounds...
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