Article
Pilot study of arbitrarily primed PCR-single stranded DNA conformation polymorphism analysis for screening genetic polymorphisms related to specific phenotypes.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2005
Maekawa Masato, Taniguchi Terumi, Uramoto Takeshi, Higashi Hitomi, Horii Toshinobu, Takeshita Akihiro, Sugimura Haruhiko, Kanamori Masao
Abstract excerpt
BACKGROUND: To investigate relationships between phenotypes and genotypes is not simple. We propose a phenotype-to-genotype screening strategy and pooled DNA system. As a pilot study of this strategy, we used arbitrarily primed polymerase chain reaction (AP-PCR) in combination with single-stranded DNA conformation polymorphism (SSCP) to screen for genetic polymorphisms associated with longevity. METHODS: Study...
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