Article
Individual single tube genotyping and DNA pooling by allele-specific PCR to uncover associations of polymorphisms with complex diseases.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2007
Casado-Díaz Antonio, Cuenca-Acevedo Rafael, Quesada José Manuel, Dorado Gabriel
Abstract excerpt
BACKGROUND: The genotyping for the study of the SNPs in different complex diseases require a great number of patients. In this sense, the determination of allele frequencies and genotypes requires a rapid and economical procedure. METHODS: The genotype has been carried out by allele-specific PCR...
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