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Article

Individual single tube genotyping and DNA pooling by allele-specific PCR to uncover associations of polymorphisms with complex diseases.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2007

Casado-Díaz Antonio, Cuenca-Acevedo Rafael, Quesada José Manuel, Dorado Gabriel

Abstract excerpt

BACKGROUND: The genotyping for the study of the SNPs in different complex diseases require a great number of patients. In this sense, the determination of allele frequencies and genotypes requires a rapid and economical procedure. METHODS: The genotype has been carried out by allele-specific PCR in single tube with the discrimination of the products of PCR by its T(m). For this purpose a GC tail was added to 5'...

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Identifiers

PMID: 16999948
DOI: 10.1016/j.cca.2006.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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