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Article

TP53*P72 allele influences negatively female life expectancy in a population of central Italy: cross-sectional study and genetic-demographic approach analysis.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 May 2013

Di Pietro Fabio, Dato Serena, Carpi Francesco M, Corneveaux Jason J, Serfaustini Simona, Maoloni Sebastiano, Mignini Fiorenzo, Huentelman Matthew J, Passarino Giuseppe, Napolioni Valerio

Abstract excerpt

The association of TP53 P72R (rs1042522) with longevity remains uncertain and varies with ethnicity. Here, we tested its association with longevity in a cross-sectional population of Central Italy (18-106 years, N = 1,072), by integrating demographic information and frequency data to account for the different survival rates between sexes through the application of a genetic-demographic approach. rs1042522 affects...

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Identifiers

PMID: 23125046
DOI: 10.1093/gerona/gls223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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