Article
Polymorphisms in the superoxidase dismutase genes reveal no association with human longevity in Germans: a case-control association study.
Biogerontology - 1 Dec 2013
Gentschew Liljana, Flachsbart Friederike, Kleindorp Rabea, Badarinarayan Nandini, Schreiber Stefan, Nebel Almut
Abstract excerpt
The role of superoxide dismutases (SODs) in aging and oxidative stress regulation has been widely studied and there is growing evidence that imbalances in these processes influence lifespan in several species. In humans, genetic polymorphisms in SOD genes may play an important role in the development of age-related diseases and genetic variation in SOD2 is thought to be associated with longevity. These...
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