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Article

Growth inhibitory effect of celecoxib and rofecoxib on human colorectal carcinoma cell lines.

Anticancer research - 1 Jan 2000

Buecher Bruno, Bouancheau Delphine, Broquet Alexis, Bezieau Stéphane, Denis Marc G, Bonnet Christian, Heymann Marie-Françoise, Jarry Anne, Galmiche Jean-Paul, Blottière Hervé M

Abstract excerpt

BACKGROUND: Epidemiological studies have revealed a protective effect of NSAIDs, which principally target cyclooxygenase (COX)-1 and COX-2, on the development of colorectal cancer. Increased expression of COX-2 was shown in colorectal adenocarcinoma. However, some effects were shown to be COX-independent. Here, we compared two selective COX-2 inhibitors for their effect on the growth of colorectal tumour cells in...

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PMID: 15816542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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