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The Combined Anti-Tumor Effects of 5-Fluorouracil and Neurokinin Receptor Inhibitor, Aprepitant, against Colorectal Cancer: In vitro and In vivo Study

2023-11-29

Abstract excerpt

<h4>Background: </h4> Colorectal cancer (CRC) is one of the world's largest health concerns with growing global incidence and mortality. The potential value of the neurokinin-1 receptor as a therapeutic target has been reported in several tumor types, including CRC. Here we examined the potential anti-tumor effects of a clinically approved neurokinin -1 receptor antagonist, aprepitant, alone and its combination wi...

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Literature Corpus work
13cfdfa0-4ab2-582c-846d-2e38e45c7fcd
DOI
10.21203/rs.3.rs-3666066/v1
Open publication

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