Article
FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon.
EMBO reports - 1 May 2005
Angelini Sandra, Deitermann Sandra, Koch Hans-Georg
Abstract excerpt
Co-translational membrane targeting of proteins by the bacterial signal-recognition particle (SRP) requires the specific interaction of the SRP-ribosome nascent chain complex with FtsY, the bacterial SRP receptor (SR). FtsY is homologous to the SRalpha-subunit of the eukaryotic SR, which is tethered to the endoplasmic-reticulum membrane by its interaction with the integral SRbeta-subunit. In contrast to SRalpha,...
Topics
- Bacterial Proteins
- Cell Membrane
- Escherichia coli
- Escherichia coli Proteins
- Mutation
- Protein Binding
- Protein Structure, Tertiary
- Receptors, Cytoplasmic and Nuclear
- SEC Translocation Channels
- Signal Recognition Particle
