Article
A molecular modeling study of the interaction between SRP-receptor complex and peptide translocon.
Biochemical and biophysical research communications - 12 Dec 2008
Chen Shifei, Fan Yi, Shen Xueling, Sun Peng, Jiang Guosong, Shen Yi, Xue Wenfei, Li Yongquan, Chen Xin
Abstract excerpt
The signal recognition particle (SRP) mediated protein translocation pathway is universal and highly conserved in all kingdoms of life. Significant progresses have been made to understand its molecular mechanism, yet many open questions remain. A structure model, showing how nascent peptide inserts into peptide translocon with the help of SRP protein Ffh and its receptor FtsY, is desired to facilitate our...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Calcium-Binding Proteins
- Computer Simulation
- Escherichia coli Proteins
- Membrane Glycoproteins
- Models, Molecular
- Mutation
- Protein Structure, Tertiary
- Protein Transport
- Receptors, Cytoplasmic and Nuclear
- Receptors, Peptide