Article
Genetic maps of microsatellite and single-nucleotide polymorphism markers: are the distances accurate?
Genetic epidemiology - 1 May 2003
Leal Suzanne M
Abstract excerpt
Genetic maps play an important role in gene mapping. Inaccurate genetic maps can hinder gene mapping by biasing lod scores and reducing the power to map a trait to a particular region. Although sequence-based physical maps can provide a unique order for markers, they do not provide information on genetic map distances. By simulation studies, I investigated how many meioses are necessary to accurately estimate...
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