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Article

Case-control association studies in mixed populations: correcting using genomic control.

Human heredity - 1 Jan 2004

Shmulewitz Dvora, Zhang Junying, Greenberg David A

Abstract excerpt

OBJECTIVE: Case-control association studies in mixed populations can result in spurious disease-marker associations if subpopulation disease prevalence and marker frequencies both differ. Genomic control (GC) uses neutral loci to correct for spurious association (due to population stratification), but how well this works remains undetermined. METHODS: We simulated and mixed populations with different disease and...

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PMID: 15812171
DOI: 10.1159/000083541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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