Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations.

doi:10.1038/sj.ejhg.5201275

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Overdispersion of allele frequency differences between populations: implications for meta-analyses of genotypic disease associations.

European journal of human genetics : EJHG - 1 Jan 2005

Molony Cliona M, Fitzgerald Anthony P, Shields Denis C

Abstract excerpt

Methods correcting case-control studies of genetic polymorphisms for unmeasured genetic population substructure by modelling the variation at a number of variant loci provide no standard and easily implemented approach to meta-analysis, which is a key to understanding the effects of minor genotypic risks on complex diseases. A correction of the odds ratio estimate and its confidence interval is shown to be easy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to CpG Islands
Share to Gene Frequency
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 15470368
DOI: 10.1038/sj.ejhg.5201275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.