Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders.

The Journal of infectious diseases - 1 May 2005

Tarr Philip E, Taffé Patrick, Bleiber Gabriela, Furrer Hansjakob, Rotger Margalida, Martinez Raquel, Hirschel Bernard, Battegay Manuel, Weber Rainer, Vernazza Pietro, Bernasconi Enos, Darioli Roger, Rickenbach Martin, Ledergerber Bruno, Telenti Amalio

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms in genes involved in lipoprotein and adipocyte metabolism may explain why dyslipidemia and lipoatrophy occur in some but not all antiretroviral therapy (ART)-treated individuals. METHODS: We evaluated the contribution of APOC3 -482C-->T, -455T-->C, and 3238C-->G; epsilon 2 and epsilon 4 alleles of APOE; and TNF -238G-->A to dyslipidemia and lipoatrophy by longitudinally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Apolipoprotein C-III

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins C

Share to CD4 Lymphocyte Count

Share to Hypertriglyceridemia

Share to Multivariate Analysis

Share to Switzerland

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 15809899
DOI: 10.1086/429295

Genes

APOC3
APOE
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling the influence of APOC3, APOE, and TNF polymorphisms on the risk of antiretroviral therapy-associated lipid disorders.PMID 15809899Read ↗

Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy.Semantic proximity Read ↗

Impact of genetic polymorphisms on the risk of lipid disorders in patients on anti-HIV therapy.Semantic proximity Read ↗

Contribution of APOA5, APOC3, CETP, ABCA1 and SIK3 genetic variants to hypertriglyceridemia development in Mexican HIV-patients receiving antiretroviral therapy.Semantic proximity Read ↗

Polymorphisms in LPL, CETP, and HL protect HIV-infected patients from atherogenic dyslipidemia in an allele-dose-dependent manner.Semantic proximity Read ↗

Impact of genetic factors on dyslipidemia in HIV-infected patients starting antiretroviral therapy.Semantic proximity Read ↗

Dyslipidemia in HIV-infected individuals: from pharmacogenetics to pharmacogenomics.Semantic proximity Read ↗

Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study.Semantic proximity Read ↗

Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy.Semantic proximity Read ↗

Toxicogenetics of antiretroviral therapy: genetic factors that contribute to metabolic complications.Semantic proximity Read ↗

Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy.Semantic proximity Read ↗

Association between polymorphisms in genes involved in lipid metabolism and immunological status in chronically HIV-infected patients.Semantic proximity Read ↗

Genetic markers associated to dyslipidemia in HIV-infected individuals on HAART.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.