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Dyslipidemia in HIV-infected individuals: from pharmacogenetics to pharmacogenomics.

Pharmacogenomics - 1 Apr 2010

Tarr Philip E, Rotger Margalida, Telenti Amalio

Abstract excerpt

HIV-infected individuals may have accelerated atherogenesis and an increased risk for premature coronary artery disease. Dyslipidemia represents a key pro-atherogenic mechanism. In HIV-infected patients, dyslipidemia is typically attributed to the adverse effects of antiretroviral therapy. Nine recent genome-wide association studies have afforded a comprehensive, unbiased inventory of common SNPs at 36 genetic...

Topics

Anti-HIV Agents
Coronary Artery Disease
Diabetes Mellitus
Dyslipidemias
Genome, Human
HIV Infections
Humans
Lipids
Pharmacogenetics
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20350140
DOI: 10.2217/pgs.10.35

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