Article
Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy.
AIDS (London, England) - 12 Sept 2008
Zanone Poma Barbara, Riva Agostino, Nasi Milena, Cicconi Paola, Broggini Valentina, Lepri Alessandro Cozzi, Mologni Daniela, Mazzotta Francesco, Monforte Antonella D'Arminio, Mussini Cristina, Cossarizza Andrea, Galli Massimo
Abstract excerpt
OBJECTIVE AND DESIGN: The present study aims at evaluating the influence of genetic polymorphisms on antiretroviral therapy (ART)-associated lipodystrophy. We included in the study 255 ICoNA. patients and we assessed the distribution of Fas -670 AG polymorphism, ApoC3 -455 CT and -482 CT polymorphisms, C161T silent substitution in the PPAR gamma gene, the Adrenergic beta3 Receptor (ARbeta3) codon 64 TC variant,...
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