Article
Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy.
Pharmacogenetics and genomics - 1 Sept 2007
Arnedo Mireia, Taffé Patrick, Sahli Roland, Furrer Hansjakob, Hirschel Bernard, Elzi Luigia, Weber Rainer, Vernazza Pietro, Bernasconi Enos, Darioli Roger, Bergmann Sven, Beckmann Jacques S, Telenti Amalio, Tarr Philip E
Abstract excerpt
BACKGROUND: HIV-1 infected individuals have an increased cardiovascular risk which is partially mediated by dyslipidemia. Single nucleotide polymorphisms in multiple genes involved in lipid transport and metabolism are presumed to modulate the risk of dyslipidemia in response to antiretroviral therapy. METHODS: The contribution to dyslipidemia of 20 selected single nucleotide polymorphisms of 13 genes reported in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
