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Article

Impact of genetic polymorphisms on the risk of lipid disorders in patients on anti-HIV therapy.

Clinical chemistry and laboratory medicine - 1 Jan 2007

Bonnet Eric, Genoux Annelise, Bernard Jacques, Fauvel Josette, Massip Patrice, Perret Bertrand

Abstract excerpt

Active anti-HIV therapy can induce hypertriglyceridemia, low high-density lipoprotein (HDL) and insulin resistance, eventually accompanied by clinical lipodystrophy, associated loss of subcutaneous adipose tissue and an increase in abdominal adiposity. The frequency of these metabolic disorders is approximately 50% and host genetic factors might confer particular susceptibility. Variants of apolipoproteins (apo)...

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Share to Antiretroviral Therapy, Highly Active
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 17617020
DOI: 10.1515/CCLM.2007.140

Genes

APOC3
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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