Article
Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study.
Circulation. Cardiovascular genetics - 1 Dec 2009
Rotger Margalida, Bayard Cornelia, Taffé Patrick, Martinez Raquel, Cavassini Matthias, Bernasconi Enos, Battegay Manuel, Hirschel Bernard, Furrer Hansjakob, Witteck Andrea, Weber Rainer, Ledergerber Bruno, Telenti Amalio, Tarr Philip E
Abstract excerpt
BACKGROUND: HIV-infected individuals have an increased risk of myocardial infarction. Antiretroviral therapy (ART) is regarded as a major determinant of dyslipidemia in HIV-infected individuals. Previous genetic studies have been limited by the validity of the single-nucleotide polymorphisms (SNPs) interrogated and by cross-sectional design. Recent genome-wide association studies have reliably associated common...
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