Article
Contribution of APOA5, APOC3, CETP, ABCA1 and SIK3 genetic variants to hypertriglyceridemia development in Mexican HIV-patients receiving antiretroviral therapy.
Pharmacogenetics and genomics - 1 Apr 2022
Bautista-Martínez Jonathan Saúl, Mata-Marín José Antonio, Sandoval-Ramírez Jorge Luis, Chaparro-Sánchez Alberto, Manjarrez-Téllez Bulmaro, Uribe-Noguez Luis Antonio, Gaytán-Martínez Jesús, Núñez-Armendáriz Mireya, Cruz-Sánchez Arcenio, Núñez-Rodríguez Nohemí, Iván Martínez-Abarca, Morales-González Georgina Selene, Álvarez-Mendoza Juan Pablo, Pérez-Barragán Edgar, Ríos-De Los Ríos Jussara, Contreras-Chávez Gerson Gabriel, Tapia-Magallanes Denisse Marielle, Ribas-Aparicio Rosa Maria, Díaz-López Mónica, Olivares-Labastida Azucena, Gómez-Delgado Alejandro, Torres Javier, Miranda-Duarte Antonio, Zenteno Juan C, Pompa-Mera Ericka Nelly
Abstract excerpt
OBJECTIVE: To investigate the impact of single nucleotide polymorphisms (SNPs) from APOA5, APOC3, CETP, ATP binding cassette transporter A1 and SIK3 genes in the development of hypertriglyceridemia in HIV patients under antiretroviral therapy. MATERIAL AND METHODS: A case-control study was developed. Leukocytic genomic DNA was extracted and genotyping for SNPs rs662799, rs964184, rs5128, , ,...