Article
Promoter and functional polymorphisms of HTR2C and suicide victims.
Genes, brain, and behavior - 1 Jul 2009
Videtic Alja, Peternelj Tina T, Zupanc Tomaz, Balazic Joze, Komel Radovan
Abstract excerpt
In Europe, the countries with the highest suicide rates form a so-called J-curve, which starts in Finland and extends down to Slovenia-a country with one of the world's highest suicide rates. So far, the strongest association between suicide and genes has been shown for the serotonergic system. A functional polymorphism 68G>C (Cys23Ser) and a promoter polymorphism-995G>A of serotonin receptor 2C (HTR2C) have...
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