Article
Suicide, stress and serotonin receptor 1A promoter polymorphism -1019C>G in Slovenian suicide victims.
European archives of psychiatry and clinical neuroscience - 1 Jun 2009
Videtic Alja, Zupanc Tomaz, Pregelj Peter, Balazic Joze, Tomori Martina, Komel Radovan
Abstract excerpt
Implication of serotonergic system in suicide and suicide attempts has been discussed for several years. One of the most abundant serotonin receptors in the mammalian brain is the receptor 1A (5-HT1A); studies of its polymorphisms and suicide have provided very inconsistent results so far. The suggestion that the G allele depresses HTR1A autoreceptor expression, and therefore reduces serotonergic...
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