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Article

The CFTR gene and regulation of its expression

1 Apr 2005

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator gene (CFTR) shows clear temporal and developmental regulation of its expression. However, there are few well-defined regulatory elements that control this pattern of expression, and their mechanism of action is poorly understood. We review the structure and organization of the CFTR gene and what is known about its regulation. The CFTR gene promoter is...

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PMID: 15806593
DOI: 10.1002/ppul.20199

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