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Article

Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues

1 Jan 1993

Abstract excerpt

An improved understanding of the expression of the cystic fibrosis gene (CFTR) will assist our approach to preventing the organ damage caused by cystic fibrosis (CF). We have studied the expression of CFTR in human fetal tissues at different gestational ages using in situ hybridization to detect CFTR mRNA. CFTR was principally expressed in less differentiated cells of endodermal origin. The highest levels were...

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PMID: 7684640
DOI: 10.1093/hmg/2.3.219

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