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Article

Genetic segregation analysis of recurrent, early-onset major depression: evidence for single major locus transmission.

American journal of medical genetics - 8 Mar 2002

Maher Brion S, Marazita Mary L, Zubenko Wendy N, Spiker Duane G, Giles Donna E, Kaplan Barry B, Zubenko George S

Abstract excerpt

Coordinated efforts are now underway to identify susceptibility genes for unipolar major depressive disorder (MDD) and related disorders. These studies have focused on recurrent, early-onset MDD (RE-MDD), thought to be the most familial form of this disorder. The goal of this study was to conduct a complex segregation analysis of recurrent MDD and other major mood disorders aggregating in families identified by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11857584
DOI: 10.1002/ajmg.10158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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