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Article

Miz1 is required for early embryonic development during gastrulation.

Molecular and cellular biology - 1 Nov 2003

Adhikary Sovana, Peukert Karen, Karsunky Holger, Beuger Vincent, Lutz Werner, Elsässer Hans-Peter, Möröy Tarik, Eilers Martin

Abstract excerpt

Miz1 is a member of the POZ domain/zinc finger transcription factor family. In vivo, Miz1 forms a complex with the Myc oncoprotein and recruits Myc to core promoter elements. Myc represses transcription through Miz1 binding sites. We now show that the Miz1 gene is ubiquitously expressed during mouse embryogenesis. In order to elucidate the physiological function of Miz1, we have deleted the mouse Miz1 gene by...

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Brachyury Protein
Cyclin-Dependent Kinase Inhibitor p15
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p57
Fetal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-myc

T-Box Domain Proteins

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Identifiers

PMID: 14560010
DOI: 10.1128/MCB.23.21.7648-7657.2003
PMCID: PMC207589

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Miz1 is required for early embryonic development during gastrulation.PMID 14560010Read ↗

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