Article
Association of aromatase (CYP 19) gene variation with features of hyperandrogenism in two populations of young women.
Human reproduction (Oxford, England) - 1 Jul 2005
Petry C J, Ong K K, Michelmore K F, Artigas S, Wingate D L, Balen A H, de Zegher F, Ibáñez L, Dunger D B
Abstract excerpt
BACKGROUND: Aromatase catalyses the conversion of androgens to estrogens and thus variation in the aromatase gene could contribute to female syndromes of androgen excess, such as precocious pubarche (PP) and polycystic ovarian syndrome (PCOS). METHODS: Two groups, one case-control containing girls from Barcelona, Spain with PP (n = 186) or healthy controls (n = 71), and the other a population study of young women...
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