Article
Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss.
The British journal of dermatology - 1 Aug 2009
Yip L, Zaloumis S, Irwin D, Severi G, Hopper J, Giles G, Harrap S, Sinclair R, Ellis J
Abstract excerpt
BACKGROUND: Female pattern hair loss (FPHL) is a common trait in which androgens and oestrogens may have a pathogenic role. The aromatase enzyme converts androgens to oestrogens in scalp hair follicles and is differentially expressed in balding and nonbalding scalps of women. Sequence variation in the gene encoding aromatase, CYP19A1, might influence the risk of developing FPHL. OBJECTIVES: To examine the role of...
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