Article
Concerted auto-regulation in yeast endosomal t-SNAREs.
The Journal of biological chemistry - 3 Jun 2005
Paumet Fabienne, Rahimian Vahid, Di Liberto Maurizio, Rothman James E
Abstract excerpt
In yeast, the assembly of the target (t)-SNAREs [Tlg2p/Tlg1p,Vti1p] and [Pep12p/Tlg1p,Vti1p] with the vesicular (v)-SNARE Snc2p promotes endocytic fusion. Here, selected mutations and truncations of SNARE proteins were tested in an in vitro fusion assay to identify potential regulatory regions in these proteins, and two distinct regions were found. The first is represented by the combined effect of the three...
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