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Ykt6 functionally overlaps with vacuolar and exocytic R-SNAREs in the yeast Saccharomyces cerevisiae.

The Journal of biological chemistry - 1 May 2024

Watanabe Hayate, Urano Shingo, Kikuchi Nozomi, Kubo Yurika, Kikuchi Ayumi, Gomi Katsuya, Shintani Takahiro

Abstract excerpt

The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex forms a 4-helix coiled-coil bundle consisting of 16 layers of interacting side chains upon membrane fusion. The central layer (layer 0) is highly conserved and comprises three glutamines (Q) and one arginine (R), and thus SNAREs are classified into Qa-, Qb-, Qc-, and R-SNAREs. Homotypic vacuolar fusion in Saccharomyces...

Topics

Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Vacuoles
R-SNARE Proteins
Membrane Fusion
Exocytosis
SNARE Proteins
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38588809
DOI: 10.1016/j.jbc.2024.107274
PMCID: PMC11091695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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