Article
Correlation of polymorphism in the interleukin-1 receptor antagonist gene intron 2 with alcoholic liver disease.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Feb 2005
Chen Wei-Xing, Xu Gen-Yun, Yu Chao-Hui, Wang Ping, Yu Min, Xu Ping, Liu You-Shi, Li You-Ming
Abstract excerpt
BACKGROUND: Interleukin-1 receptor antagonist (IL-1ra) can inhibit the pro-inflammatory effects of IL-1, which recently has been thought to involve the pathogenesis of alcoholic liver disease (ALD). This study was undertaken to determine whether there is any association between IL-1ra gene polymorphism and ALD in a Chinese population. METHODS: The polymorphism of IL-1ra gene intron 2 (VNTR) was assessed in 165...
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