Article
Interleukin-1 receptor antagonist haplotype associated with prostate cancer risk.
British journal of cancer - 22 Aug 2005
Lindmark F, Zheng S L, Wiklund F, Bälter K A, Sun J, Chang B, Hedelin M, Clark J, Johansson J-E, Meyers D A, Adami H-O, Isaacs W, Grönberg H, Xu J
Abstract excerpt
IL1-RN is an important anti-inflammatory cytokine that modulate the inflammation response by binding to IL1 receptors, and as a consequence inhibits the action of proinflammatory cytokines IL1alpha and IL1beta. In this study, we hypothesise that sequence variants in the IL1-RN gene are associated with prostate cancer risk. The study population, a population-based case-control study in Sweden, consisted of 1383...
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